Evaluation on the Efficacy of Bronchodilator Nebulization Via High Flow Nasal Cannula

NCT03091504 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2018-04-04

No results posted yet for this study

Summary

High-humidity nasal cannula (HFNC) has been shown to be effective in improving oxygenation and avoiding intubation in multiple randomized control trials, it is also suitable and feasible for long term use. Aerosol delivery via HFNC will minimize interruptions and improve patient compliance, bench study and radionuclide imaging study done in healthy volunteers demonstrated that aerosol can be effectively delivered using HFNC. This study aims to evaluate the efficacy of bronchodilator delivered via HFNC in chronic pulmonary obstructive disease or asthma patients.

Conditions

  • High Flow Nasal Cannula

Interventions

DEVICE

High flow nasal cannula

High flow nasal cannula is a soft and flexible nasal prongs with adjustable head strap fits over the patient's ears, it delivers a broad variety of gas flows directly into the nares without gas jetting.

DRUG

Albuterol Sulfate

Albuterol is a short acting inhaled bronchodilator

Sponsors & Collaborators

  • People's Hospital of Xinjiang Uygur Autonomous Region

    collaborator OTHER
  • Rush University Medical Center

    lead OTHER

Principal Investigators

  • Minghua Zhao, MD · People's Hospital of Xinjiang Uygur Autonomous Region

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-09-04
Primary Completion
2018-03-31
Completion
2018-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03091504 on ClinicalTrials.gov