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Clinical Evaluation of Smoker Periodontal Subjects After Lactobacillus-reuteri Probiotics and Antibiotics Therapy

NCT04209777 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2019-12-24

No results posted yet for this study

Summary

It is a clinical trial conducted on smokers with chronic periodontitis in which the participants are divided into two groups and one group is provided with antibiotics while the other with probiotics as an adjunct to non-surgical therapy. The participants were assessed for change in probing pocket depths, attachment loss, bleeding on probing, plaque index and gingival index after 1-month and 3-month period.

Conditions

  • Periodontal Diseases
  • Smoking

Interventions

DRUG

Probiotic Blend Chewable Tablet

Lactobacillus-reuteri probiotics were used as an experimental drug.

DRUG

Antibiotics

Amoxicillin capsules 500mg and metronidazole tablets 400mg antibiotics were used as an active comparator.

Sponsors & Collaborators

  • Dow University of Health Sciences

    lead OTHER

Principal Investigators

  • Shahbaz Ahmed, BDS/FCPS · Dow University of Health Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-07-08
Primary Completion
2019-04-16
Completion
2019-05-06

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04209777 on ClinicalTrials.gov