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Serial MRI Scans During Radiation Therapy

NCT04188535 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 149

Last updated 2025-08-26

No results posted yet for this study

Summary

This is a phase 1 study to determine the feasibility and utility of using serial magnetic resonance imaging (MRI) to assess treatment response during and after radiation therapy (standard of care cancer treatment) for participants with advanced esophageal cancer, glioblastoma, prostate cancer, vulvar cancer or pediatric glioma.

The research study procedures include three MRI scans (one before, one during, and one after standard of care cancer radiation therapy) for participants with advanced esophageal cancer, glioblastoma, prostate cancer, vulvar cancer or pediatric glioma.

The research study procedures include:

* Screening for eligibility
* Three MRI scans

Conditions

  • Glioblastoma
  • Esophageal Cancer
  • Radiotherapy
  • Magnetic Resonance Imaging
  • MRI
  • Prostate Cancer
  • Vulvar Cancer
  • Pediatric Glioblastoma Multiforme

Interventions

DIAGNOSTIC_TEST

MRI IMAGING

Imaging with MRI will be performed as per disease site standards.

Sponsors & Collaborators

Principal Investigators

  • Jonathan Leeman, MD · Dana-Farber Cancer Institute

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-15
Primary Completion
2030-07-31
Completion
2030-07-31
FDA Device
Yes

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04188535 on ClinicalTrials.gov