MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy

NCT02031237 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 52

Last updated 2019-07-26

Study results available
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Summary

This study aims to assess changes in vascular permeability in the brain tumor, and in the surrounding brain, due to radiation therapy, using Magnetic Resonance Imaging (MRI).

Conditions

Interventions

RADIATION

Single Fraction Stereotactic Radiosurgery (SRS)

Intervention will not be assigned by the investigator. Treatment determination will be made prior to study enrollment.

RADIATION

Fractionated Whole Brain Radiation Therapy (WBRT)

Intervention will not be assigned by the investigator. Treatment determination will be made prior to study enrollment.

RADIATION

Fractionated Stereotactic Radiation Therapy (FSRT)

Intervention will not be assigned by the investigator. Treatment determination will be made prior to study enrollment.

DEVICE

Magnetic Resonance Imaging (MRI) Assessments

MRI scans will include a routine clinical MRI series.

Sponsors & Collaborators

  • University of Michigan Rogel Cancer Center

    lead OTHER

Principal Investigators

  • Yue Cao, Ph.D. · University of Michigan Rogel Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-04-30
Primary Completion
2014-05-31
Completion
2014-12-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02031237 on ClinicalTrials.gov