Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities
NCT00589095 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 5
Last updated 2014-07-02
Summary
The purpose of this study is to determine whether dynamic contrast enhanced MRI (DCE MRI) and high diffusion weighting MRI may be used to distinguish between favorable and unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be correlated with histopathologic findings and clinical responses to radiation therapy with or without chemotherapy.
Conditions
Interventions
- OTHER
-
dynamic contrast enhanced magnetic resonance imaging
dynamic contrast enhanced MRI using contrast agent gadodiamide
Sponsors & Collaborators
-
Yale University
lead OTHER
Principal Investigators
-
Jonathan Knisely, M.D. · Yale University
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-11-30
- Primary Completion
- 2011-08-31
- Completion
- 2011-08-31
Countries
- United States
Study Locations
More Related Trials
-
Correlative Analysis Between Magnetic Resonance Spectroscopy (MRS) and Essential Clinicobiological Data in Glioblatoma Multiforme (GBM)
NCT07211841 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Differentiation of Progression From Treatment Effects in High-Grade Gliomas: A Clinical Trial With Multimodality MR Imaging
NCT03102203 ·Status: UNKNOWN
-
Impact of iMRI on the Extent of Resection in Patients With Newly Diagnosed Glioblastomas
NCT02379572 ·Status: COMPLETED ·Phase: NA
-
Non-invasive Glioma Characterization Through Molecular Imaging
NCT03684109 ·Status: RECRUITING ·Phase: NA
-
Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme
NCT01604590 ·Status: COMPLETED
-
Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastoma
NCT04143425 ·Status: COMPLETED
-
Correlation Between the Genetic and Neuroimaging Signatures in Newly Diagnosed Glioblastoma Patients Before Surgery
NCT02590497 ·Status: WITHDRAWN ·Phase: NA
-
Assessment of Optune Therapy for Patients With Newly Diagnosed Glioblastoma Using Advanced MRI
NCT03297125 ·Status: ACTIVE_NOT_RECRUITING
-
Image-derived Prediction of Response to Chemo-radiation in Glioblastoma
NCT02329795 ·Status: TERMINATED
-
Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas
NCT01225003 ·Status: COMPLETED
-
Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors
NCT00581906 ·Status: ACTIVE_NOT_RECRUITING
-
Radiogenomic and Prognosis Analysis in Glioma
NCT04122521 ·Status: UNKNOWN
-
fMRI Study of Functional Reorganization in Glioma Patients
NCT05019196 ·Status: UNKNOWN
-
Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases
NCT05911230 ·Status: RECRUITING ·Phase: NA
-
Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI
NCT02843230 ·Status: COMPLETED
-
MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma
NCT00756106 ·Status: TERMINATED ·Phase: NA
-
Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients
NCT01579253 ·Status: UNKNOWN
-
Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study
NCT02941302 ·Status: UNKNOWN ·Phase: NA
-
18F-PSMA PET/CT for Visualization of Glioblastoma Multiforme
NCT04588454 ·Status: UNKNOWN ·Phase: NA
-
Gallium Ga 68-DOTATATE PET/CT in Predicting Tumor Growth in Patients With Meningiomas
NCT03953131 ·Status: COMPLETED ·Phase: PHASE1
-
Laboratory Study of Early Tumor Markers in the Peripheral Blood of Glioblastoma Multiforme Patients
NCT01135875 ·Status: COMPLETED
-
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas
NCT00274755 ·Status: COMPLETED ·Phase: PHASE2
-
Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study
NCT06002711 ·Status: RECRUITING
-
Brain Glioma Registry Combining Clinical and Imaging Information
NCT02619890 ·Status: RECRUITING
-
Feasibility Study of 68Ga-PSMA PET-CT and 18F-FDOPA PET-CT in Glioblastoma's Patients
NCT03903419 ·Status: UNKNOWN ·Phase: NA