MedTrace Logo

Brain Imaging of Cognition Inn Schizophrenia and Depression

NCT04159662 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2026-03-23

No results posted yet for this study

Summary

Schizophrenia and depression are among the most disabling disorders in all of medicine. Cognitive deficits play a key role in patients' disability, affecting their capacity to contribute actively to society by sustaining employment or academic activity. Moreover, cognitive difficulties tend to persist even after the stabilization of other clinical symptoms. Verbal memory and emotion regulation are two important cognitive domains that are impaired in schizophrenia and depression and are associated with patients' functional outcomes. In this study, brain imaging is used to investigate the brain mechanisms underlying these cognitive deficits in these populations.

Conditions

  • Schizophrenia / Schizoaffective Disorder
  • Depression / Major Depressive Disorder

Sponsors & Collaborators

  • The Royal Ottawa Mental Health Centre

    lead OTHER

Principal Investigators

  • Synthia Guimond, PhD · Royal Ottawa Mental Health Centre

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-12
Primary Completion
2026-10-01
Completion
2026-10-01

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04159662 on ClinicalTrials.gov