Database Registry for Neural Network Biomarkers in Psychosis
NCT01409109 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-04-23
Summary
Several observations have been made with magnetic resonance imaging (MRI) that characterize brain connections and brain function in individuals with schizophrenia and other mental disorders. For example, research investigating schizophrenia focuses on the dysfunction of connections within and between the medial temporal lobe and the prefrontal cortex as well as other pertinent brain regions. This database registry will allow for the collection of clinical interview data, behavioral data, blood, magnetic resonance imaging (MRI) data, and functional magnetic resonance imaging (fMRI) data on individuals with and without mental disorders to better understand how connections in the brain and various brain regions function differently while volunteers perform various cognitive tasks. This is an observational study that is being conducted to collect data and place it in a registry for current and future investigational questions related to imaging in mental disorders.
Conditions
- Schizophrenia
- Schizoaffective Disorder
Sponsors & Collaborators
-
National Institute of Mental Health (NIMH)
collaborator NIH -
University of Texas Southwestern Medical Center
lead OTHER
Principal Investigators
-
Carol A. Tamminga, M.D. · UT Southwestern
-
Elena Ivleva, M.D., Ph.D. · UT Southwestern
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-03-31
- Primary Completion
- 2029-04-30
- Completion
- 2029-04-30
Countries
- United States
Study Locations
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