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Evaluation of Efficacy of Sodium Monofluorophosphate (SMPF) Toothpastes on Enamel Lesion Remineralisation

NCT04155658 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2020-05-18

No results posted yet for this study

Summary

Double-blind, randomized, 3 group in situ study to assess effect of three toothpastes on enamel remineralization, as measured by change in integrated mineral loss (∆∆Z). The study will examine the efficacy of an experimental sodium monofluorophosphate (SMFP) toothpaste, a standard SMFP toothpaste and a negative control toothpaste with no fluoride.

Conditions

  • Enamel Caries

Interventions

OTHER

Experimental Toothpaste containing 1450ppm SMFP

Experimental Toothpaste containing 1450ppm SMFP

OTHER

Toothpaste containing 1450ppm SMFP

Toothpaste containing 1450ppm SMFP

OTHER

Toothpaste with no fluoride

Toothpaste with no fluoride

Sponsors & Collaborators

  • Indiana University

    collaborator OTHER

  • Unilever R&D

    lead INDUSTRY

Principal Investigators

  • Domenick T Zero, DDS, MS · Indiana University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-25
Primary Completion
2020-04-30
Completion
2020-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04155658 on ClinicalTrials.gov