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Exploratory Study to Evaluate the Efficacy of an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity

NCT01831817 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2015-03-26

Study results available
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Summary

The purpose of this exploratory study is to compare the treatment effect on dentinal hypersensitivity of a tubule occluding dentifrice as measured by Schiff and Tactile sensitivity. This proof of concept study will compare the test dentifrice with three other treatment groups.

Conditions

  • Dentinal Hypersensitivity

Interventions

DRUG

5% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice

Calcium sodium phosphosilicate dentifrice (5% w/w) and 1500 ppm F as sodium monofluorophosphate

DRUG

0% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice

No calcium sodium phosphosilicate and 1500 ppm F as sodium monofluorophosphate

DRUG

Sodium monofluorophosphate dentifrice

Sodium monofluorophospate dentifrice (1000 ppm F)

DRUG

Sodium Fluoride dentifrice

Dentifrice containing 1100ppm F as sodium fluoride

Sponsors & Collaborators

Principal Investigators

  • GSK Clinical Trials · GlaxoSmithKline

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-01-31
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01831817 on ClinicalTrials.gov