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Comparison of the Effect of Microchip and Density Gradient Methods in Intrauterine Insemination Cycles

NCT04144244 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 176

Last updated 2020-02-12

No results posted yet for this study

Summary

Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm separation in IVF and IUI cycles leads to the increase of reactive oxygen radicals in sperm and this leads to sperm DNA fragmentation. Studies comparing Percoll and microfluidic chip method in terms of sperm, embryo quality and pregnancy rates are limited. In this context, it is aimed to investigate the effect of Percoll or Microfluidic Chip Technology on the quality of sperms and embryos obtained with these sperms and their pregnancy rates prospectively.

Conditions

  • Infertility Unexplained
  • Infertility, Male

Interventions

OTHER

MicroFluidic Sperm Sorting Chips

sperm selection of IUI treatment

OTHER

Gradient-Density Centrifugation

sperm selection of IUI treatment

Sponsors & Collaborators

  • Bezmialem Vakif University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-15
Primary Completion
2020-05-15
Completion
2020-07-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

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View NCT04144244 on ClinicalTrials.gov