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Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates

NCT04744025 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2022-10-03

No results posted yet for this study

Summary

This research is being done to determine if using a microfluidics chamber, a device used to process sperm, will be effective in improving the rates of embryos with normal chromosomes (structures that carry genetic information) during in vitro fertilization (IVF) treatment. The investigators hypothesize that this device is effective at improving rates of normal chromosomes among embryos.

Conditions

Interventions

DEVICE

Microfluidics chamber

Unwashed sperm will be placed into the inlet chamber of the microfluidics device. The most motile sperm will swim to the outlet chamber, and these sperms will be used for intracytoplasmic sperm injection (ICSI) into the eggs.

OTHER

Density Gradient Centrifugation

Sperm will be washed and centrifuged according to standard protocol, and these washed sperm will be used for ICSI.

Sponsors & Collaborators

  • The Center for Advanced Reproductive Services, P.C.

    collaborator OTHER

  • ZyMot Fertility

    collaborator UNKNOWN

  • Lawrence Engmann

    lead OTHER

Principal Investigators

  • Lawrence Engmann, MD · UConn Health

  • Alison Bartolucci, PhD · The Center for Advanced Reproductive Services, P.C.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
42 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-13
Primary Completion
2022-08-15
Completion
2022-12-31
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04744025 on ClinicalTrials.gov