Acute Effects of Sitting and Physical Activity on Brain Health

Summary

The specific aim of this study is to understand how a working day composed of prolonged sitting, sitting regularly interrupted by light aerobic exercise or resistance exercise affects an important mechanism underpinning healthy brain functions, namely cerebral blood flow. It is primarily focused on investigating these effects in ecologically valid conditions, i.e. activity patterns that closely resemble a typical day at the office.

Conditions

• Healthy Adults

Interventions

BEHAVIORAL

Prolonged sitting with social break

Participants are required to sit for three hours (reading is permitted), with a toilet break in between. Every thirty minutes participants will have a short social break. Test day begins at 7:30 with pretest measures, followed by the intervention at about 9:00, which will end around 12:00, with subsequent posttest measures.

BEHAVIORAL

Prolonged sitting with walk break

Participants are required to sit for three hours (reading is permitted), with a toilet break in between. Every thirty minutes participants will have a physical activity break, where they will perform a brisk walk for about three minutes on a treadmill at a predetermined speed and grade based on the fitness test performed during the familiarization session. Test day begins at 7:30 with pretest measures, followed by the intervention at about 9:00, which will end around 12:00, with subsequent posttest measures.

BEHAVIORAL

Prolonged sitting with simple resistance activities

Participants are required to sit for three hours (reading is permitted), with a toilet break in between. Every thirty minutes participants will have a physical activity break, where they will perform simple resistance activities following a video for about three minutes. Test day begins at 7:30 with pretest measures, followed by the intervention at about 9:00, which will end around 12:00, with subsequent posttest measures.

Sponsors & Collaborators

• The Knowledge Foundation

  collaborator UNKNOWN

• ICA-gruppen

  collaborator UNKNOWN

• Intrum AB

  collaborator UNKNOWN

• SATS

  collaborator UNKNOWN

• Monark Exercise

  collaborator UNKNOWN

• Itrim

  collaborator UNKNOWN

• The Swedish School of Sport and Health Sciences

  lead OTHER

Principal Investigators

• Maria Ekblom, PhD · The Swedish School of Sport and Health Sciences (GIH)

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

40 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-05-13

Primary Completion

2020-03-13

Completion

2020-03-13

Countries

• Sweden

Study Locations