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Brain Power: Resistance Training and Cognitive Function

NCT00426881 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 155

Last updated 2017-10-04

No results posted yet for this study

Summary

Primary Objectives:

1\. To ascertain whether a 12-month, twice-weekly or once-weekly resistance training (RT) program will significantly improve executive function in community-dwelling women aged 65 to 75 years old compared with a 12-month, twice-weekly stretch and relax (S \& R) program (shame exercise). We will assess executive function by standard neuropsychological tests.

Secondary Objectives:

1. To describe the neural mechanisms that underpin the observed changes in executive function associated with a 12-month, twice-weekly or once-weekly RT training (by using functional magnetic resonance imaging (fMRI)).
2. To investigate whether RT-induced changes in executive function are independently associated with changes in physiological fall risk profile.
3. To investigate the dose response of RT (resistance training) on bone health as measured by dual energy x-ray and peripheral quantitative computed tomography.
4. To conduct a one-year follow-up after the formal cessation of the resistance training programs to determine the persisting effect of resistance training on cognitive performance, cortical plasticity, physiological falls risk, and bone health.

Conditions

  • Healthy

Interventions

BEHAVIORAL

Exercise Training

Twice weekly resistance training for 52 weeks.

BEHAVIORAL

Exercise training

Once weekly resistance training for 52 weeks.

BEHAVIORAL

Exercise training

Twice weekly resistance training for 52 weeks.

Sponsors & Collaborators

  • Michael Smith Foundation for Health Research

    collaborator OTHER

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Teresa Liu-Ambrose, Ph.D · University of British Columbia

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
65 Years
Max Age
75 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2008-06-30
Completion
2008-06-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00426881 on ClinicalTrials.gov