Prospective Multicenter Study for Early Evaluation of Acute Chest Pain
NCT04122573 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 10000
Last updated 2019-11-29
Summary
In this study, clinical database and blood sample bank of acute chest pain (ACP) will be established at chest pain center of multi-center hospital. To explore new biomarkers and screen clinical indicators with effective risk stratification and prognostic evaluation for ACP through proteomics technology and statistics methods. Risk stratification and short-term and long-term prognostic evaluation models for high-risk ACP will be established using large data analysis.
Conditions
- Chest Pain
- Acute Aortic Dissection
- Pulmonary Embolism
- Acute Myocardial Infarction Type 1
- Acute Coronary Syndrome
Interventions
- DIAGNOSTIC_TEST
-
Coronary angiography
Acute chest pain patients, suspected acute coronary syndrome, are diagnosed by coronary angiography.
- DIAGNOSTIC_TEST
-
CT angiography of aorta
Acute chest pain patients, suspected acute aortic dissection, are diagnosed by gold standard of CTA.
- DIAGNOSTIC_TEST
-
CT angiography of pulmonary arteries.
Acute chest pain patients, suspected acute pulmonary embolism, are diagnosed by gold standard of CTA.
- DIAGNOSTIC_TEST
-
Electrocardiogram
All patients with acute chest pain will subject to ECG examination within 10 minutes of admission, which can quickly screen ST-segment elevation myocardial infarction.
- DIAGNOSTIC_TEST
-
Cardiac Troponin
Dynamic changes of cardiac troponin I and/or T will be used in the diagnosis of acute myocardial infarction
Sponsors & Collaborators
-
West China Hospital
lead OTHER
Principal Investigators
-
Dongze Li, MBBS · Emergency Department, West China Hospital, Sichuan University
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-11-01
- Primary Completion
- 2021-10-31
- Completion
- 2022-10-31
Countries
- China
Study Locations
More Related Trials
-
High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification
NCT02984436 ·Status: COMPLETED
-
Troponin to Risk Stratify Patients for Computed Tomography Coronary Angiography
NCT04549805 ·Status: COMPLETED
-
A Study on the Peripheral Blood in Patients With Acute Coronary Syndrome
NCT06955143 ·Status: RECRUITING
-
Blood Biomarker Discovery by Raman Spectroscopy in Acute Aortic Dissection
NCT05206032 ·Status: UNKNOWN
-
Correlation of Biomarkers With the Presence and Severity of Coronary Artery Disease
NCT05015270 ·Status: COMPLETED
-
Troponin in Acute Chest Pain to Risk Stratify and Guide EffecTive Use of Computed Tomography Coronary Angiography
NCT03952351 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
TTE Improves Clinical Management of Stable Chest Pain
NCT07063147 ·Status: RECRUITING
-
Assessment of the Diagnostic Performance of the Detection System and Establishment of an Intelligent and Rapid Triage Model
NCT06864676 ·Status: NOT_YET_RECRUITING
-
A Multicenter Study on Early Diagnosis of NSTE-ACS Patients Based on Machine Learning Model
NCT04682756 ·Status: UNKNOWN
-
Clinical Features, Treatment Mode and Health Outcomes of Chest Pain Patients in China (CHANGE)
NCT04014972 ·Status: UNKNOWN
-
Hs-cTnI Diagnosis of NSTE-ACS Patients in China
NCT03734796 ·Status: UNKNOWN
-
Biomarkers in Acute Cardiac Care
NCT02355457 ·Status: RECRUITING
-
Acute Myocardial Infarction Study in Northeastern China
NCT04451967 ·Status: UNKNOWN
-
Study on High-sensitivity Troponin 0h/1h for Rapid Diagnosis of Non-ST-segment Elevation Myocardial Infarction in the Chinese Population
NCT03331549 ·Status: UNKNOWN
-
Diagnostic Evaluation of Out-of-hospital High-sensitivity Troponin I in Patients Presenting Chest Pain
NCT04950244 ·Status: COMPLETED
-
Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department
NCT00907231 ·Status: WITHDRAWN
-
Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain
NCT00705458 ·Status: COMPLETED ·Phase: NA
-
Evaluation of hsTnI in the Management of Patients With Chest Pain in the Emergency Department
NCT02789904 ·Status: COMPLETED
-
CCT for Comprehensive Risk Stratification Following STEMI
NCT06020209 ·Status: RECRUITING ·Phase: NA
-
A Cohort of Patients Undergoing Percutaneous Coronary Intervention
NCT05719545 ·Status: RECRUITING
-
Biomarkers and Risk Scores for Risk Stratification of Unstable Angina
NCT03628586 ·Status: UNKNOWN
-
An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
NCT03076580 ·Status: UNKNOWN
-
Assessment of New Biomarkers in the Management and Triage of Patients With Chest Pain and Suspicion of Non ST Elevation Acute Coronary Syndrome.
NCT00769574 ·Status: COMPLETED ·Phase: NA
-
Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio
NCT07110298 ·Status: COMPLETED
-
A Prospective Pilot Study to Evaluate a New Marker of Ischemia in Chest Pain Triage
NCT02608255 ·Status: COMPLETED ·Phase: NA