GLP-1 drugs discovered accidentally in anglerfish research now treat conditions beyond diabetes including kidney disease, sleep apnea, and addiction. The global diabetes therapeutics market is projected to reach $241.5 billion by 2030, growing at 12.4% annually.
Mavacamten significantly reduces heart obstruction in adolescents with hypertrophic cardiomyopathy, with patients experiencing a 48.5 mm Hg drop in blockage compared to minimal change in placebo groups. The drug also lowered blood markers indicating heart damage and showed promise in slowing disease progression. Separate real-world data confirms mavacamten's effectiveness as monotherapy across diverse patient populations.
The European Commission approved MYQORZO (aficamten) for treating symptomatic obstructive hypertrophic cardiomyopathy in adults, completing global regulatory approvals following FDA and China NMPA clearances. First European launch planned in Germany in Q2 2026.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07579182 |
Hormones, Outcomes, and Pain Pathways in Exercise Study |
NOT_YET_RECRUITING | PHASE1 |
| NCT07536932 |
Triage and Recognition of Acute Aortic Dissection in Chest Pain by Electrocardiogram-Artificial Intelligence |
NOT_YET_RECRUITING | |
| NCT07532564 |
Risk Factors, Costs, and Impacts of ED Boarding |
COMPLETED | |
| NCT07435168 |
CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis |
RECRUITING | NA |
| NCT07432620 |
Artificial Intelligence Stress Echo (FINESSE) Project |
ACTIVE_NOT_RECRUITING | |
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Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions |
NOT_YET_RECRUITING | NA |
| NCT07247669 |
Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands for Time-dependent Pathology at the Emergency and Urgent Care Coordination Center (CCUE). |
RECRUITING | |
| NCT07235657 |
AI-Assisted Interpretation of Cardiac CT in the Emergency Department |
NOT_YET_RECRUITING | NA |
| NCT07192965 |
ECG-less Coronary Computed Tomography Angiography in the Management of Patients Presenting With High-troponin Chest Pain |
RECRUITING | NA |
| NCT07140419 |
Coronary Computed Tomographic Angiography Combined With CT-FFR in Intermediate-Risk Chest Pain Patients. |
NOT_YET_RECRUITING | NA |
