Correlation of Biomarkers With the Presence and Severity of Coronary Artery Disease
NCT05015270 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 900
Last updated 2022-03-29
Summary
The development of coronary artery disease is multifactorial. Peripheral blood biomarkers paly an important role in the prediction of coronary artery disease. However, the identification of those biomarkers and their correlation with the presence and severity of coronary artery disease are unclear. The present study aims to identify the differentially expressed biomarkers from peripheral blood between normal population and patients with different disease burden confirmed by coronary angiography, and to analyze the correlation of those biomarkers with the severity of coronary artery disease. Finally, the prediction of biomarkers for clinical events.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
Medications or percutaneous coronary intervention
In this study, we will for the first analyze the correlation of proteins concentration with coronary artery disease burden. Next, the prediction of proteins for one-year clinical events will be further analyzed
Sponsors & Collaborators
-
Nanjing First Hospital, Nanjing Medical University
lead OTHER
Principal Investigators
-
Shao-Liang M Chen, MD · The First Affiliated Hospital with Nanjing Medical University
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-07-21
- Primary Completion
- 2021-12-27
- Completion
- 2021-12-30
Countries
- China
Study Locations
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