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Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty

NCT04085588 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2021-09-14

No results posted yet for this study

Summary

This study evaluates continous infusion of low-dose ketamine during intraoperative and postoperative periods at three different doses to provide postoperative analgesia in total knee arthroplasty cases. Patients enrolled randomly into one of 2, 4, 6 μg / kg / min perioperative ketamine groups. All groups were given spinal anesthesia and intravenous patient controlled anesthesia. Ketamine was started when sensorial block reached T10 dermatome level before the skin incision. By the end of the operation, in all groups, ketamine infusions were reduced by half doses. Intravenous patient-controlled analgesia device was set to 2 mg bolus morphine with no basal infusion for 48 hours during the postoperative period.

Conditions

  • Postoperative Pain

Sponsors & Collaborators

  • Mustafa Kemal University

    lead OTHER

Principal Investigators

  • Selim Turhanoglu, M.D. · Mustafa Kemal University, Medical School, 31100 Hatay, Turkey

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-04-15
Primary Completion
2021-09-02
Completion
2021-09-02

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04085588 on ClinicalTrials.gov