Effect of Ketamine Assisted Analgesia on Oxygen Supply and Oxygen Consumption in Patients After Cardiac Surgery
NCT04906915 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 112
Last updated 2021-05-28
Summary
After cardiopulmonary bypass heart surgery, with the rewarming of body temperature, the metabolic capacity of the body is enhanced, the microcirculation is opened, and tissue perfusion is increased. At the same time, the body pays off the oxygen debt formed by the low temperature and reduced blood flow in cardiopulmonary bypass, so that the tissue oxygen demand increases and oxygen consumption increases.Analgesia and sedation are important treatment measures for patients after cardiopulmonary bypass. S-isomer of ketamine and eselamine enhanced the sedation and enhanced the analgesic effect, but whether it can improve the imbalance of oxygen supply and oxygen consumption after cardiopulmonary bypass is unknown.
Conditions
- Intensive Care Unit
Interventions
- DRUG
-
The efficacy of ketamine was assessed by calculating oxygen supply and consumption
Sponsors & Collaborators
-
First People's Hospital of Chenzhou
lead OTHER
Principal Investigators
-
Dixian DX Luo, MS · Chenzhou First People Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-08
- Primary Completion
- 2022-05-31
- Completion
- 2022-05-31
Countries
- China
Study Locations
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