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Intrathecal Morphine in Knee Arthroplasty

NCT00695045 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2008-06-11

No results posted yet for this study

Summary

This study is designed to explore the efficacy lower doses of intra-spinal morphine for pain relief and side effect profiles of same in the setting of Total Knee Replacement.We hypothesized that a dose greater than that used in Total Hip Replacement was needed and wished to find a dose which was effective but had a low side effect profile.

Conditions

  • Pain, Postoperative
  • Arthroplasty, Replacement, Knee

Interventions

DRUG

intra thecal morphine

100 mcg intrathecal morphine given once .

DRUG

intra thecal morphine

200 mcg intrathecal morphine given once

DRUG

intra thecal morphine

300 mcg intrathecal morphine given once

Sponsors & Collaborators

  • University College Hospital Galway

    lead OTHER

Principal Investigators

  • Patrick D Hassett, MD · Department of Anaesthesia, UCHG

  • John Laffey, MD · Department of Anaesthesia,UCHG

  • Brian Kinirons, MD · Dept of Anaesthesia , UCHG

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-07-31
Primary Completion
2007-01-31
Completion
2007-04-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00695045 on ClinicalTrials.gov