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Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

NCT00562627 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 102

Last updated 2011-08-08

Study results available
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Summary

Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge.

The aim of this study is to:

1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee arthroplasty.
2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural analgesia.

Conditions

  • Osteoarthritis of the Knee

Interventions

DRUG

ropivacaine

intraoperative and 1. postoperative day

DRUG

adrenaline

intraoperative LIA (IV and IA) and continuous EDA

DRUG

ketorolac

intraoperative and 1. postoperative day

DRUG

morphine

intraoperative

DRUG

fentanyl

continuous postoperatively

DRUG

bupivacaine

continuous postoperatively

Sponsors & Collaborators

  • Asker & Baerum Hospital

    lead OTHER

Principal Investigators

  • Ulrich J Spreng, MD · Asker and Baerum Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-11-30
Primary Completion
2009-06-30
Completion
2009-07-31

Countries

  • Norway

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00562627 on ClinicalTrials.gov