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Neuroinflammation During ICU-associated Delirium in Critically Ill Patients and Its Association With Structural and Functional Brain Alterations: a Nested Case-control Study

NCT04078503 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2019-09-06

No results posted yet for this study

Summary

With the present study, the authors aim to improve the knowledge of the pathophysiology of ICU-related delirium. In particular, the authors would like to clarify the possible correlation between neuroinflammation, evaluated longitudinally by serum dosage of 20 different neuroinflammation biomarkers, and brain structural and functional alterations (using brain fMRI).

Conditions

  • Delirium
  • Critical Illness

Sponsors & Collaborators

  • University of Pisa

    collaborator OTHER

  • University of Turin, Italy

    collaborator OTHER

  • University of Milano Bicocca

    collaborator OTHER

  • Università degli Studi di Brescia

    collaborator OTHER

  • Mie University

    collaborator OTHER

  • Erasme University Hospital

    collaborator OTHER

  • Maastricht University

    collaborator OTHER

  • Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-25
Primary Completion
2021-03-25
Completion
2021-06-25

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04078503 on ClinicalTrials.gov