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A Bioavailability Study of Nicotine Delivered by an Electronic Vapour Product

NCT02032212 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2025-09-10

Study results available
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Summary

Electronic Vapour Products (EVPs) are a relatively new class of consumer products that are otherwise known as electronic cigarettes. These may look like conventional cigarettes but do not contain tobacco.

The 'vapour' produced by such devices typically consists of humectants (propylene glycol or glycerol), nicotine, water, and flavours.

This trial is to evaluate the pharmacokinetic profile of an EVP.

Conditions

  • Healthy Volunteers

Interventions

OTHER

EVP unflavoured

OTHER

EVP flavoured

OTHER

Nicotine inhalator

15 mg nicotine Nicorette

OTHER

Conventional cigarette

Sponsors & Collaborators

  • Imperial Brands PLC

    lead INDUSTRY

Principal Investigators

  • Girish Sharma, MD · Simbec Research

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-12-31
Primary Completion
2014-05-31
Completion
2015-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02032212 on ClinicalTrials.gov