Antimicrobial Efficacy of Four Different Irrigation Protocols
NCT03668899 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-06-29
Summary
proper disinfection of root canal system before obturation is a must for long term success of endodontic treatment, therefore a proper irrigant is mandatory, therefore investigators are studying the antibacterial effects of 4 different irrgating solutions in root canal treatment of patients diagnosed with necrotic pulps in their mandibular posterior teeth. patients will be recruited from outpatient clinic of the endodontic department in cairo university. endodontic treatment will be carried out as usual and samples from the infected root canals will be collected before and after preparation to be cultivated and analyzed at the laboratories of microbiology of faculty of medicine, cairo university
Conditions
- Dental Pulp Necrosis
Interventions
- PROCEDURE
-
irrigation
irrigation of root canals during mechanical preparation for pueposes of cleaning and disinfection
Sponsors & Collaborators
-
Cairo University
lead OTHER
Principal Investigators
-
Maha Nasr, Masters · studying for PhD in Cairo University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 22 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-01-25
- Primary Completion
- 2020-04-30
- Completion
- 2020-08-15
Countries
- Egypt
Study Locations
More Related Trials
-
Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth
NCT05988788 ·Status: COMPLETED ·Phase: NA
-
Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite
NCT04728386 ·Status: UNKNOWN ·Phase: NA
-
Chitosan,Chitosan Nanoparticles,and Chlorhexidine Gluconate, as Intra Canal Medicaments in Primary Teeth
NCT03588351 ·Status: UNKNOWN ·Phase: NA
-
Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria
NCT04035070 ·Status: UNKNOWN ·Phase: PHASE4
-
Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth
NCT05739682 ·Status: COMPLETED ·Phase: NA
-
Effect of NanoChitosan Impregnated Calcium Hydroxide as an Intracanal Medication on Postoperative Pain Intensity and Bacterial Load Reduction
NCT06253247 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars
NCT06418386 ·Status: COMPLETED ·Phase: NA
-
Clinical and Radiographic Evaluation of the Synergistic Effect of Nano Silver Particles and Calcium Hydroxide Versus Triple Antibiotic Paste as Antibacterial Agents for Lesion Sterilization and Tissue Repair (LSTR) in Necrotic Primary Molars
NCT05681221 ·Status: UNKNOWN ·Phase: NA
-
Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods
NCT06959602 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Effect of N-acetylcysteine Versus Calcium Hydroxide Used as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Levels of MMP -9 in Periapical Fluids in Patients With Necrotic Pulp
NCT05666089 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Effect of Sodium Hypochlorite Concentration on Success of Non-surgical Root Canal Treatment
NCT03288467 ·Status: COMPLETED ·Phase: NA
-
Postoperative Pain After Endodontic Irrigation Using 1.3% Versus 5.25% Sodium Hypochlorite
NCT03792217 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Antimicrobial Efficacy and Postoperative Pain After Using Silver Nanoparticles and Chitosan Nanoparticles Against Enterococcus Faecalis and Candida Albicans Biofilm
NCT06172023 ·Status: COMPLETED ·Phase: NA
-
Different Concentrations of Sodium Hypochlorite Affecting Post-endodontic Pain
NCT05840679 ·Status: UNKNOWN ·Phase: PHASE1
-
Evaluation of Antimicrobial Potency of Garlic Lemon Extract Irrigant Versus Physiological Saline Irrigant
NCT06759766 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins
NCT03312153 ·Status: UNKNOWN ·Phase: NA
-
Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars
NCT06971055 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Cryotreated Sodium Hypochlorite Irrigation At Different Consentrations in Mandibular First Molars
NCT06820996 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
NCT06926322 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Clinical and Microbiological Evaluation of 0.5% Versus 3% Sodium Hypochlorite in Root Canal Treatment
NCT02681276 ·Status: COMPLETED ·Phase: NA
-
Clinical and Radiographic Evaluation of Calcium Hypochlorite Versus Saline As Root Canal Irrigants in Pulpectomy of Primary Molars: a Randomized Clinical Trial
NCT06748781 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
NCT05146713 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain
NCT04035330 ·Status: UNKNOWN ·Phase: NA
-
Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth
NCT06310044 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Assessment of Postoperative Pain After Using Various Intracanal Medication in Patients With Necrotic Pulp
NCT03692286 ·Status: COMPLETED ·Phase: PHASE4