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Massively Parallel Sequencing to Identify Microbiological Organisms in Bronchoalveolar Lavage Fluid

NCT03995030 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2022-10-25

No results posted yet for this study

Summary

Patients who are post hematopoietic stem cell transplantation who require a bronchoalveolar lavage (BAL) for standard clinical car will have extra fluid collected and sent for massively parallel sequencing to see if it is as sensitive for detecting a microbial pulmonary infection compared to standard cultures.

Conditions

  • Pulmonary Infection

Interventions

DIAGNOSTIC_TEST

massively paralleled sequencing

Whole genome sequencing libraries will be generated and sequenced in batches on the Illumina MiSeq. FASTQ files will be demultiplexed and then aligned to microbial genomes using Phylosift.

Sponsors & Collaborators

  • New York Medical College

    lead OTHER

Principal Investigators

  • Jeremy Rosenblum, MD · New York Medical College

Eligibility

Min Age
0 Years
Max Age
29 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-15
Primary Completion
2019-01-31
Completion
2021-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03995030 on ClinicalTrials.gov