Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction
NCT06211166 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2024-01-18
Summary
A research investigation into the efficacy of digital Polymerase Chain Reaction (dPCR) for monitoring measurable residual disease (MRD) during allogeneic hematopoietic stem cell transplantation, with a focus on predicting relapse in patients diagnosed with leukemia, myelodysplastic syndromes (MDS), and related hematological conditions.
Conditions
- Acute Leukemia
- MDS
- MDS/MPN
- CML
Interventions
- DIAGNOSTIC_TEST
-
Digital PCR
digital Polymerase Chain Reaction (dPCR)
- DIAGNOSTIC_TEST
-
Quantitative PCR
Real-time Polymerase Chain Reaction (real-time PCR)
- DIAGNOSTIC_TEST
-
MFC
Multicolor Flow Cytometry
Sponsors & Collaborators
-
Peking University People's Hospital
lead OTHER
Principal Investigators
-
Xiao-jun Huang, M.D · Peking University People's Hospital
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-01-08
- Primary Completion
- 2025-12-31
- Completion
- 2027-12-31
Countries
- China
Study Locations
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