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Pathogen Identification in Pediatric Hematopoietic Stem Cell Transplant Patients With Suspected Lower Respiratory Tract Infection

NCT02926612 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2018-08-31

No results posted yet for this study

Summary

This is a multicenter prospective collection of leftover respiratory tract secretions, paired blood and NP swabs, and clinical circumstances from pediatric HCT patients, followed by next generation genomic sequencing, transcriptome analysis, protein biomarker measurement, and statistical modeling.

Conditions

Interventions

OTHER

Next Generation Genomic Sequencing

DNA and RNA are extracted from biospecimens, amplified, sequenced, and then compared to known microbe databases, allowing for quantitative identification of non-host organisms

Sponsors & Collaborators

  • St. Baldrick's Foundation

    collaborator OTHER

  • Pediatric Blood and Marrow Transplant Foundation, Inc.

    lead OTHER

Principal Investigators

  • Matthew Zinter, MD · University of California, San Francisco

Eligibility

Max Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2019-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02926612 on ClinicalTrials.gov