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Lower and Higher Load Resistance Exercise Protocols: Acute Muscle Activation and Skeletal Muscle Hypertrophy

NCT03991117 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2019-06-19

No results posted yet for this study

Summary

How much weight an individual lifts per workout does not dictate the relative increase in muscle size the individual gains following weeks of training, which is contrary to current strength training dogma. Specifically, researchers have concluded that so long as an individual performs resistance exercise with maximum effort, it is not necessary to lift with relatively heavy loads. However, other laboratories, on the basis of surface electromyography measurements, have challenged the thesis that lighter loads can result in the hypertrophy of larger, type II muscle fibres. Therefore, the purpose of this study was to combine surface electromyography measurements with direct measurements of muscle fibre activation to see if muscle fibre activation was truly dependent on load. The investigators hypothesized that all muscle fibres would be activated when the resistance exercise was performed with maximal effort.

Conditions

  • Muscle Hypertrophy
  • Muscle Fibre Activation

Interventions

BEHAVIORAL

resistance exercise

unilateral knee extensions until fatigue with varying load and speeds of contraction

Sponsors & Collaborators

Principal Investigators

  • Stuart Phillips, PhD · McMaster University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-04
Primary Completion
2016-03-01
Completion
2016-03-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03991117 on ClinicalTrials.gov