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Muscle Typology and Strength Training Adaptations

NCT05108181 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-04-12

No results posted yet for this study

Summary

The overall aim of this project is to investigate if the responsiveness to chronic resistance training is dependent on the muscle typology. In a second aim we will investigate the most optimal training frequency for slow-twitchers and fast-twitchers. For the latter we hypothesize that slow-twitchers might cope better with higher frequencies and higher volumes compared to fast-twitchers.

Male and female adult participants (18-45y) will be recruited. The subjects' muscle typology will be non-invasively estimated in the leg muscles by measurement of muscle carnosine using H-MRS. In total 21 subjects (11 slow and 10 fast subjects) will participate. Subjects will be assigned to a whole-body resistance training exercise protocol of 9 weeks in wich arm A and leg A will train 3 times per week and arm B and leg B will train 2 times per week. Before and following the training period, subjects will be subjected to different measurements (fitness level, muscle volume, strength tests, blood sampling, muscle biopsies).

Conditions

  • Muscle Fiber Type
  • Exercise
  • Training Frequency

Interventions

OTHER

Muscle typology + exercise training

Exercise training: Participants perform 9 weeks of strength training at 60% of their 1RM.

OTHER

Muscle typology + training frequency

Training frequency: leg A and arm A of the participants train 3 times per week, leg B and arm B train 2 times per week.

Sponsors & Collaborators

  • University Ghent

    lead OTHER

Principal Investigators

  • Wim Derave · University Ghent

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-09
Primary Completion
2023-12-08
Completion
2023-12-08

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05108181 on ClinicalTrials.gov