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Strategic Training to Optimize Neurocognitive Functions in Older Adults

NCT03988829 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2022-01-28

No results posted yet for this study

Summary

The goal of the present randomized control trial is to evaluate the efficacy of a novel cognitive training approach using simulated games, where older adults will learn to flexibly deploy attentional control during working memory, for prevention of Alzheimer's Disease (AD). Based on our extensive pilot work, we expect training-related enhancements in both neural and cognitive functions on a broad range of cognitive abilities due to the importance of attentional control and working memory in many types of cognition. These outcomes are widely applicable to the cognitive health and the quality of life of elderly Americans, and have further potential to offset degenerative processes common to normal aging.

Conditions

  • Cognitive Aging
  • Functional Magnetic Resonance Imaging

Interventions

BEHAVIORAL

Low-C

This is the active control group, where participants will be trained to play an experimenter developed game that requires least attentional control among all arms.

BEHAVIORAL

High-C

In this intervention, participants will be trained on this experimenter developed game which requires a lot of attentional control.

BEHAVIORAL

High-C+

A commercial video game will be used that requires a lot of demand on attentional control.

Sponsors & Collaborators

  • University of Texas Southwestern Medical Center

    collaborator OTHER

  • National Institute on Aging (NIA)

    collaborator NIH

  • The University of Texas at Dallas

    lead OTHER

Principal Investigators

  • Chandramallika Basak, PhD · The University of Texas at Dallas

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-30
Primary Completion
2021-08-31
Completion
2021-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03988829 on ClinicalTrials.gov