The Influence of Multi-domain Cognitive Training on Large-scale Structural and Functional Brain Networks in MCI
NCT03883308 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2021-05-05
Summary
The purpose of this study is to integrate advanced computational techniques and multimodal neuroimaging methods to examine the potential effects of long-term, multi-domain, online, computerized cognitive training on large-scale structural and functional brain networks in older adults with mild cognitive impairment (MCI).
Conditions
Interventions
- BEHAVIORAL
-
Multi-domain cognitive training
The cognitive exercises are designed to train executive functions and memory.
- BEHAVIORAL
-
Cross-word puzzle training
The active control group will be asked to complete a variety of crossword puzzles using the same curriculum assigned to the TG group.
Sponsors & Collaborators
-
National Institute on Aging (NIA)
collaborator NIH - lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-10-30
- Primary Completion
- 2020-09-30
- Completion
- 2020-12-01
Countries
- United States
Study Locations
More Related Trials
-
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
NCT06601933 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy of Computerized Cognitive Training in the Elderly With Mild Cognitive Impairment
NCT03577717 ·Status: TERMINATED ·Phase: NA
-
Effects of Combined Physical-cognitive Training on Cognitive Function in MCI
NCT03805620 ·Status: COMPLETED ·Phase: NA
-
Effects of 24-week Computerized Cognitive Training in Patients With MCI and AD
NCT06094452 ·Status: COMPLETED ·Phase: NA
-
Beneficial Effects of Mindfulness-based Training on Neuropsychological Outcomes in Mild Cognitive Impairment
NCT04000984 ·Status: COMPLETED ·Phase: NA
-
Effects of Exercise and Cognitive Training on Cognitive Function in Older Adults
NCT01038726 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of Cognitive Training in Older and Younger Adults
NCT06375681 ·Status: RECRUITING ·Phase: NA
-
Protocol of Multi-domain Attention Training
NCT03379519 ·Status: COMPLETED ·Phase: NA
-
Clinical Exploratory Research of Medial Prefrontal Cortex Combined With Dorsolateral Prefrontal Cortex Electrical Stimulation in the Treatment of Alzheimer's Disease
NCT05971030 ·Status: UNKNOWN ·Phase: NA
-
Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline
NCT05014893 ·Status: RECRUITING ·Phase: NA
-
Cognitive Rehabilitation During Transcranial Direct Current Stimulation
NCT03050385 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of Computerized Cognitive Training in the Elderly With Cognitive Impairment
NCT02480738 ·Status: COMPLETED ·Phase: NA
-
Nurse-led Clinics Training Program on Mild Cognitive Impairment Patients
NCT06198530 ·Status: UNKNOWN ·Phase: NA
-
Transcranial Magnetic Stimulation in Disorder of Consciousness in Acute Severe Cerebrovascular Disease Patients
NCT05670873 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Improvement of Memory in Mild Cognitive Impairment
NCT05708001 ·Status: RECRUITING ·Phase: NA
-
Dual-Task Training for People With Mild Cognitive Impairment and Mild Dementia
NCT06348810 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Pilot Study for Efficacy of Cognitive and Physical Training in Patients With Mild Cognitive Impairment
NCT06355973 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Strategic Training to Optimize Neurocognitive Functions in Older Adults
NCT03988829 ·Status: COMPLETED ·Phase: NA
-
Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity
NCT03860441 ·Status: COMPLETED ·Phase: NA
-
Investigating Dynamic Interactions in Distributed Cognitive Control Networks
NCT05927974 ·Status: RECRUITING
-
Effects of tACS Combined With CCT for Patients With MCI
NCT04135742 ·Status: UNKNOWN ·Phase: NA
-
CTA-MCI: Cognitive Control Training in Patients With Amnestic Mild Cognitive Impairment(CTA-MCI)
NCT03133052 ·Status: UNKNOWN ·Phase: NA
-
Shanghai Non-pharmacological Intervention of Mild Cognitive Impairment
NCT03119051 ·Status: UNKNOWN ·Phase: NA
-
Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment
NCT01061489 ·Status: COMPLETED ·Phase: NA
-
Brain Functional Changes Accompany Modulatory Effects of Transcranial Direct Current Stimulation in Cognitive Impairment
NCT06864910 ·Status: COMPLETED