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Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment

NCT01061489 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 65

Last updated 2016-07-14

No results posted yet for this study

Summary

Age-related cognitive decline is unavoidable. However, recent results of neuroplasticity-based research show that neuroplasticity-based training and physical activity might have the potential to decelerate or even reverse effects of aging and age-related cognitive impairments. Little is known whether these results also apply to pathological processes of aging such as mild cognitive impairment (MCI) and dementia.

This multi-center study aims at investigating efficiency and feasibility of a neuroplasticity-based auditory discrimination training and a physical fitness training for patients suffering from mild cognitive impairment or mild Alzheimer's disease (Mini Mental State Examination, MMSE \> 19). Evaluation will include neuropsychological testing, electroencephalography (EEG) and magnetic resonance imaging (MRI) measurements as well as blood and liquor analyses.

Conditions

  • Mild Cognitive Impairment (MCI)
  • Mild Alzheimer's Disease

Interventions

OTHER

auditory discrimination training

10-week neuroplasticity-based training (5 days/week, 1 hour each, PC-based), training at home

OTHER

physical movement training

10-week training, small groups (2 days/week, 1 hour each) plus homework (3 days/week)

Sponsors & Collaborators

  • University of Ulm

    collaborator OTHER

  • University of Konstanz

    lead OTHER

Principal Investigators

  • Iris-Tatjana Kolassa, Prof. Dr. · Clinical and Biological Psychology, University of Ulm

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2013-03-31
Completion
2013-03-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01061489 on ClinicalTrials.gov