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PaO2/FiO2*PEEP (P/FP) Ratio and Mortality in Acute Respiratory Distress Syndrome.

NCT03946150 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 4361

Last updated 2020-03-26

No results posted yet for this study

Summary

The PaO2/FiO2 (P/F) ratio is same for all the Positive End Expiratory Pressure (PEEP) ≥ to 5. This P/F ratio misleads the severity of disease without the knowledge of set PEEP. The Oxygenation status is actually worse when the patient is using high PEEP.

P/F Ratio doesn't include PEEP in the calculation.The P/F ratio doesn't show the severity of the disease appropriate for the set PEEP.

PaO2/(FiO2 X PEEP) P/FP Ratio is a new Formula which addresses this gap to appropriately calculate the severity of the disease by including PEEP in the formula.

This formula is used to predict mortality for different severities of ARDS.

Conditions

  • Adult Respiratory Distress Syndrome

Interventions

DIAGNOSTIC_TEST

P/FP Ratio

PaO2/Fio2 X PEEP

Sponsors & Collaborators

  • National University Health System, Singapore

    lead OTHER

Principal Investigators

  • Sunitha PalaniDurai · National University Health System, Singapore

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2019-05-05
Completion
2020-03-03

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03946150 on ClinicalTrials.gov