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GapCO2 and Respiratory Rate in Patients Under Volume Mechanical Ventilation

NCT02867943 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2016-08-18

No results posted yet for this study

Summary

As an approximate of the difference between venous-to-arterial CO2 tension (∆PCO2), ∆PCO2 is proportional to CO2 production and inversely related to cardiac output (Fick equation). Anaerobic CO2 production is thought to occur when tissue hypoxia is present, mostly because of buffering of bicarbonate ions by the protons produced in excess secondary to the hydrolysis of adenosine triphosphate. Therefore ∆PCO2 has been proposed as a marker of tissue hypoxia.

Conditions

  • Shock

Interventions

OTHER

Effects of respiratory rate on gapCO2

respiratory rate was started at 10 breaths/min and added by 2 breaths/min every 60 min up to 16 breaths/min

Sponsors & Collaborators

  • 105 Hospital of Chinese People's Liberation Army

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2016-10-31
Completion
2016-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02867943 on ClinicalTrials.gov