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Effect of REST in the Alzheimer Disease Continuum

NCT03884023 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2022-03-23

No results posted yet for this study

Summary

The investigators assume that REST gene polymorphism affects REST protein concentration, and REST protein concentration in peripheral blood is related to cognitive function and hippocampus. In this current study, REST protein content and gene polymorphism will be obtained in peripheral blood in AD and normal control. The effect of REST gene polymorphism on REST protein concentration will be discovered.The relationship between REST protein concentration and cognitive function will be found, as well as the relationship between REST protein concentration and hippocampus.

Conditions

Sponsors & Collaborators

  • Dongzhimen Hospital, Beijing

    lead OTHER

Principal Investigators

  • Tian Jinzhou, MD,PhD · Dongzhimen Hospital, Beijing

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-28
Primary Completion
2020-11-30
Completion
2020-11-30

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03884023 on ClinicalTrials.gov