Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect
NCT06396260 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-01-29
Summary
The investigators aim to elucidate characteristics of structural and functional brain connectivity in patients with amyotrophic lateral sclerosis (ALS) and pseudobulbar affect (PBA) using diffusion kurtosis imaging (DKI) and magnetoencephalography (MEG).
Conditions
- Amyotrophic Lateral Sclerosis
- Pseudobulbar Affect
Interventions
- OTHER
-
Diffusion Kurtosis Imaging (DKI)
Non-invasive MRI sequence which extracts information of diffusion signals from complex brain tissue
- OTHER
-
Resting State Magnetoencephalography
Non-invasive method of measuring resting state brain activity through magnetoencephalography (MEG)
Sponsors & Collaborators
-
University of Aarhus
collaborator OTHER -
Aalborg University Hospital
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-05-26
- Primary Completion
- 2026-10-31
- Completion
- 2026-12-31
Countries
- Denmark
Study Locations
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