Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect

NCT06396260 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-01-29

No results posted yet for this study

Summary

The investigators aim to elucidate characteristics of structural and functional brain connectivity in patients with amyotrophic lateral sclerosis (ALS) and pseudobulbar affect (PBA) using diffusion kurtosis imaging (DKI) and magnetoencephalography (MEG).

Conditions

Interventions

OTHER

Diffusion Kurtosis Imaging (DKI)

Non-invasive MRI sequence which extracts information of diffusion signals from complex brain tissue

OTHER

Resting State Magnetoencephalography

Non-invasive method of measuring resting state brain activity through magnetoencephalography (MEG)

Sponsors & Collaborators

  • University of Aarhus

    collaborator OTHER
  • Aalborg University Hospital

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-05-26
Primary Completion
2026-10-31
Completion
2026-12-31

Countries

  • Denmark

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06396260 on ClinicalTrials.gov