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Biochemical Makers for Outcome After Pediatric out-of Hospital Cardiac Arrest

NCT03873662 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 4

Last updated 2020-11-30

No results posted yet for this study

Summary

This single-center study will validate serum, imaging and clinical markers to determine outcome of pediatric patients early after Out-of-Hospital cardiac arrest (OHCA). Results are expected to add to the field of postresuscitation care of these children. The validation of markers will provide clinicians with the tools to assess the severity of neurological impairment after hypoxic injury to the brain early after OHCA.

Conditions

  • Out-Of-Hospital Cardiac Arrest

Interventions

DIAGNOSTIC_TEST

Blood sample

Biochemical markers will be recorded as follows: as soon as possible after the arrival of the patient and insertion of a intravenous line, blood will be drawn for the analysis of arterial blood gases, which are a standard test in patients admitted to emergency department. Blood will be analysed in a bed-side analyzer. Serum lactate and base-excess (BE) will be documented from this blood sample. Another blood sample will be drawn parallelly for biochemical tests which will be sent to the laboratory. These tests standard in patients admitted to emergency department. Serum concentration of NSE and S100B protein will be analysed and recorded from this sample. A sample of blood for the evaluation of the early dynamics of the serum concentration of NSE and S100B will be redrawn after 12 and 48/24 hours after admitting the patient.

Sponsors & Collaborators

  • Brno University Hospital

    lead OTHER

Principal Investigators

  • Petr Stourac, assoc.Prof.MD.Ph.D · University Hospital Brno

Eligibility

Min Age
14 Days
Max Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-05-17
Primary Completion
2020-10-31
Completion
2020-10-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03873662 on ClinicalTrials.gov