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Out-of-hospital Cardiac Arrest (OHCA) Biomarkers

NCT03112486 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2020-05-08

No results posted yet for this study

Summary

Few early prognostic indicators are currently available for patients' families and clinicians following out of hospital cardiac arrest (OHCA), and blood biomarkers may be of prognostic value in these cases. Brain tissue is highly dependent upon aerobic respiration, and oxygen deprivation result in irreversible neuronal cell injury. Peptides released into the blood by injured neuronal cells can be measured to estimate degree of injury, and potentially predict long term neurological outcome.

Conditions

  • Neurological Outcome
  • Cardiac Arrest
  • Out-Of-Hospital Cardiac Arrest
  • Brain Anoxia Ischemia
  • Hypoxia, Brain
  • Hypoxia-Ischemia, Brain
  • Cardiac Arrest With Successful Resuscitation
  • Cardiac Arrest, Out-Of-Hospital
  • Brain Injuries

Interventions

PROCEDURE

blood draw

Blood draws will be collected via venipuncture or IV at hours 0, 6, 12, 18, 24, 48, 72, 96, 120, 144 (10 draws total). Each draw would be approximately 20 mL of blood (but no less than 10 mL).

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Joseph A Tyndall, MD, MPH · Chairman Department Emergency Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-26
Primary Completion
2020-01-28
Completion
2020-01-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03112486 on ClinicalTrials.gov