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NGF, TrKA,p75NTR in Men With ED and Diabetes With or Without MS

NCT03862547 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2019-03-05

No results posted yet for this study

Summary

To evaluate the level of NGF,TrKA and p75NTR in patientd with erectile dysfunction and diabetes with or without metabolic syndrome

Conditions

Interventions

DIAGNOSTIC_TEST

A peripheral blood sample from the cubital vein

Evaluation of NGF and Cytokine levels A portion of each blood sample and medium conditioned by PBMC will be used for the enzyme immunoassay of NGF and pro and anti-inflammatory cytokine levels (TNF alfa and IL-10). Expression analysis of TrKA and p75NTR receptors and intracellular cytokines in PBMCs The remaining part of each blood sample and PBMC of the in vitro experiment will be used for the cytofluorimetric evaluation of the expression of TrKA, p75NTR and the pro and anti-inflammatory cytokines and reactive oxygen species.

Sponsors & Collaborators

  • Ester Illiano, MD

    collaborator UNKNOWN

  • Mario Rende,Full Professor

    collaborator UNKNOWN

  • Alessandra Psitilli, Researcher

    collaborator UNKNOWN

  • Anna Stabile, Researcher

    collaborator UNKNOWN

  • University Of Perugia

    lead OTHER

Principal Investigators

  • Ester Illiano, MD · University Of Perugia

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-30
Primary Completion
2019-12-30
Completion
2020-01-30

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03862547 on ClinicalTrials.gov