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Validation of Biomarkers of Diabetic Nephropathy in Type I Diabetic Children

NCT02164279 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2020-09-23

No results posted yet for this study

Summary

About 30 to 40% of patients suffering from type I diabetes are at risk of developing a diabetic nephropathy (DN) leading more or less rapidly to an end-stage renal disease. Nowadays, the microalbuminuria is the most often used clinical parameter for possible onset of DN. However, it is a late (because it permits to detect a renal disease already present), non-specific and low sensitive biomarker.

Therefore the main objective of this study is to identify early urinary biomarkers predictive of DN in children with type I diabetes, before the appearance of a microalbuminuria.

Conditions

  • Type 1 Diabetes Mellitus With Diabetic Nephropathy

Interventions

OTHER

Urinary sample collection

urinary sample collection will be done at the inclusion visit for the assessment of the microalbuminuria ( \< or \> than 100mg/L)

Sponsors & Collaborators

  • Laboratory Inserm U858 Team 5 - RF-lab

    collaborator UNKNOWN

  • University Hospital, Toulouse

    lead OTHER

Principal Investigators

  • Stephane DECRAMER, PhD · University Hospital, Toulouse

Eligibility

Min Age
6 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2016-05-25
Completion
2016-05-25

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02164279 on ClinicalTrials.gov