Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation
NCT03860129 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2019-03-01
Summary
The MIRUS system (TIM, Andernach, Germany) as well as the AnaConDa uses a reflector to conserve volatile anaesthetics (VA). Both systems can be paired with ICU ventilators, but MIRUS features an automated control of end-tidal VA concentrations (etVA). We compare depth of 0.5 MAC inhalational long-term sedation with Isoflurane (ISO), Sevoflurane (SEVO) or Desflurane (DES).
Conditions
- Intensive Care Unit Syndrome
Interventions
- DRUG
-
Isoflurane
Group A: Isoflurane (0.5 MAC)
- DRUG
-
Sevoflurane
Group B: Sevoflurane (0.5 MAC)
- DRUG
-
Desflurane
Group C: Desflurane (0.5 MAC)
Sponsors & Collaborators
-
Ruhr University of Bochum
lead OTHER
Principal Investigators
-
Thomas Weber, PhD · Ruhr University of Bochum, Germany
Study Design
- Allocation
- RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-12-10
- Primary Completion
- 2017-05-05
- Completion
- 2017-05-31
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