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Insufficient Oxygenation in Septic Patients

NCT03842722 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 81

Last updated 2024-05-08

No results posted yet for this study

Summary

This study will describe the change of mitochondrial oxygen tension (mitoPO2) compared to traditional parameters of oxygenation and oxygen balance in the first 24 hours of septic patients admitted to the intensive care unit of an academic hospital. The mitoPO2 will be measured on prespecified measurement moments in the ICU. With each measurement moment, arterial and central venous blood gasses will be taken too.

Conditions

  • Sepsis
  • Critical Care
  • Mitochondria
  • Oxygen
  • Fluid Therapy

Interventions

DEVICE

Protoporphyrin IX - Triplet State Lifetime Technique

Protoporphyrin IX - Triplet State Lifetime Technique is a way to measure mitochondrial oxygen tension in a non-invasive way at bedside.

Sponsors & Collaborators

  • Leiden University Medical Center

    collaborator OTHER

  • Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research

    lead OTHER

Principal Investigators

  • Johanna G van der Bom, MD, PhD · Leiden University Medical Center

  • M S Arbous, MD, PhD · Leiden University Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-13
Primary Completion
2023-09-28
Completion
2023-09-28

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03842722 on ClinicalTrials.gov