Microcirculatory Oxygen Uptake in Sepsis
NCT02430142 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 102
Last updated 2018-05-02
Summary
Forearm vasoocclusive testing (VOT) will be performed with laser-doppler spectrophotometry system in septic patients on ICU. Microcirculatory oxygen uptake will be checked for prognostic value and for associations with tissue hypoxia markers and high central venus saturations.
Conditions
- Sepsis
- Severe Sepsis
- Septic Shock
Interventions
- OTHER
-
Vasoocclusive testing
Forearm vasoocclusive testing with a laser-doppler spectrophotometry system, transpulmonary thermodilution and blood sampling;
Sponsors & Collaborators
-
Universitätsmedizin Mannheim
lead OTHER
Principal Investigators
-
Manfred Thiel, Prof. Dr. med. · Department of Anaesthesiology and Surgical Intensive Care, University Medical Centre of Mannheim
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-04-30
- Primary Completion
- 2016-10-31
- Completion
- 2017-08-01
Countries
- Germany
Study Locations
More Related Trials
-
Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis
NCT04644302 ·Status: COMPLETED
-
Vasopressor Use Improves Macrocirculation, But What Are Its Effects on Microcirculation?
NCT07312071 ·Status: COMPLETED ·Phase: NA
-
Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock
NCT01310790 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Lactate Clearance Oriented Haemodynamic Therapy on the Outcome of Patients With Septic Shock
NCT02566460 ·Status: COMPLETED ·Phase: NA
-
Targeted Exercise Intervention to Reduce Morbidity and Mortality in Sepsis
NCT04938531 ·Status: COMPLETED ·Phase: NA
-
VTE Incidence in Severe Sepsis and Septic Shock
NCT02353910 ·Status: COMPLETED
-
Outcome Predictors in Patients With Severe Sepsis and Optimized Central Venous Oxygen Saturation
NCT01362829 ·Status: COMPLETED
-
Minimal Volume for a Fluid Challenge in Septic Patients
NCT02447042 ·Status: COMPLETED ·Phase: NA
-
Shock Indices Use for Early Mortality From Septic Shock
NCT05088109 ·Status: UNKNOWN
-
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
NCT03728998 ·Status: COMPLETED ·Phase: NA
-
Survey of Non-resuscitation Fluids in Septic Shock
NCT03438097 ·Status: COMPLETED
-
Effect of Different Strategies for Titrating a High MAP on Microcirculation
NCT02085291 ·Status: COMPLETED ·Phase: PHASE4
-
German Lactat Clearance in Severe Sepsis
NCT01929772 ·Status: COMPLETED
-
Venoarterial PCO2 Difference /Arteriovenous O2 Content Difference Ratio as Goal of Early Septic Shock Therapy
NCT01877798 ·Status: UNKNOWN ·Phase: NA
-
Observational Study About the Use of Perfusion Index to Use Vasopressor in Sepsis
NCT06860438 ·Status: RECRUITING
-
Critical Closing Pressure and PCO₂ Gap in Fluid Resuscitation for Septic Shock
NCT07043192 ·Status: ACTIVE_NOT_RECRUITING
-
Sepsis, Severe Sepsis and Septic Shock Detection by Breath Analysis
NCT03497182 ·Status: COMPLETED ·Phase: NA
-
Muscle Lactate and Lactate to Pyruvate Ratio Clearance in Septic Shock Patients
NCT03700346 ·Status: COMPLETED ·Phase: NA
-
Glycocalyx and Microcirculation in Sepsis
NCT03960307 ·Status: COMPLETED
-
Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients
NCT05080543 ·Status: UNKNOWN ·Phase: PHASE1
-
Microcirculatory Guided Goal Directed Fluid Therapy in Septic Shock; a Feasibility Study
NCT03898674 ·Status: UNKNOWN ·Phase: NA
-
Proadrenomedullin and Microcirculation in Monitoring Organ Dysfunction in Patient With Infection
NCT03931967 ·Status: COMPLETED
-
Insufficient Oxygenation in Septic Patients
NCT03842722 ·Status: COMPLETED
-
The Effect of Remote Ischemic Conditioning on the Microcirculation in Sepsis
NCT04644926 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Fluid Responseveness in Sepsis and Its Correlation to CVP
NCT05612529 ·Status: TERMINATED