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Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis

NCT00541827 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2013-09-27

No results posted yet for this study

Summary

The primary aim of the study is to demonstrate that mitochondrial dysfunction occurs in both skeletal muscle and circulating platelets of severely septic and septic shock ICU-admitted patients. Secondary aims are to clarify the pathogenesis and the clinical relevance of mitochondrial damage during sepsis.

Conditions

  • Severe Sepsis
  • Septic Shock

Sponsors & Collaborators

  • European Society of Intensive Care Medicine

    collaborator OTHER

  • Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

    lead OTHER

Principal Investigators

  • Luciano Gattinoni, MD · Ospedale Maggiore Policlinico Mangiagalli e Regina Elena

  • Alessandro Protti, MD · Ospedale Maggiore Policlinico Mangiagalli e Regina Elena

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-10-31
Primary Completion
2011-08-31
Completion
2012-08-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00541827 on ClinicalTrials.gov