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Quantification of Bacterial DNA in Sepsis

NCT03782454 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2019-01-29

No results posted yet for this study

Summary

The purpose of this study is to evaluate whether bacterial DNA clearance measured with droplet digital Polymerase Chain Reaction (ddPCR) can be used as a measure of bacterial load in septic intensive care patients. Furthermore, the aim is to examine a possible relation between clearance of bacterial DNA and clinical outcome in the septic patient, and the relationship between concentration of beta-lactam antibiotics and the clearance of bacterial DNA.

Conditions

  • Septic Shock
  • Sepsis Bacterial
  • Sepsis

Interventions

DIAGNOSTIC_TEST

Blood sampling

Blood samples taken every third hour during the first 48 hours of intensive care

Sponsors & Collaborators

  • Region Örebro County

    lead OTHER

Principal Investigators

  • Jan Källman, PhD · Region Örebro County

  • Hans Hjelmqvist, Phd · Region Örebro County

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-07
Primary Completion
2021-12-31
Completion
2022-05-31

Countries

  • Sweden

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03782454 on ClinicalTrials.gov