MedTrace Logo

Examining the Impact of Blood Flow Restricted Aerobic Exercise on PGC-1α mRNA Expression in Young Healthy Males

NCT03717948 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2019-07-15

No results posted yet for this study

Summary

This crossover study investigates the effects of restricting arterial blood flow during cycling exercise on PGC-1α and its upstream signalling pathways. In a randomized order, participants will exercise once for 30 minutes with restricted blood flow and then will exercise once for 30 minutes with no blood flow restriction.

Conditions

  • Mitochondrial Biogenesis

Interventions

OTHER

BFR Exercise

Participants will exercise on a recumbent bike placed on a 45 degree incline (BFR).

OTHER

CTL Exercise

Participants will exercise on a recumbent bike placed on flat ground (CTL).

Sponsors & Collaborators

  • Queen's University

    lead OTHER

Principal Investigators

  • Brendon J Gurd, PhD · Queen's University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2019-01-28
Completion
2019-01-28

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03717948 on ClinicalTrials.gov