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Skeletal Muscle and Adipose Tissue Responses After Acute Exercise: Comparing Effects of Three Different Intensities

NCT05365334 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2024-07-26

No results posted yet for this study

Summary

The study will assess the exercise-induced changes in chromatin accessibility and gene expression in a cell type-specific manner in skeletal muscle from healthy adults in response to exercise at three different intensities - 1) low-intensity continuous exercise, 2) moderate-intensity continuous exercise, and 3) high-intensity interval exercise.

Conditions

  • Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities
  • Relationship Between the Cellular Responses in Skeletal Muscle and the Changes in the Metabolomic Profile
  • Changes Within Adipose Tissue in Response to Exercise at the Three Different Intensities

Interventions

BEHAVIORAL

Low intensity exercise session

subjects will exercise at 30% maximal oxygen consumption (VO2max) for 45-60 minutes

BEHAVIORAL

Moderate intensity exercise session

subjects will exercise at 65% maximal oxygen consumption (VO2max) for 30-45 minutes

BEHAVIORAL

High intensity exercise session

subjects will completed 10x1minute exercise intervals at maximal oxygen consumption (VO2max) with 1 minute active recovery between

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-12-13
Primary Completion
2023-06-23
Completion
2023-06-23

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05365334 on ClinicalTrials.gov