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Correlation Between Oral Health and Systemic Inflammation (COHESION)

NCT03641989 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 112

Last updated 2020-02-20

No results posted yet for this study

Summary

COHESION is a randomized trial targeting reduction of systemic inflammation through an oral hygiene regimen incorporating a plaque-disclosing toothpaste and a control toothpaste.

Conditions

Interventions

OTHER

Plaque disclosing toothpaste

Plaque identifying toothpaste with a FDA-registered seed-extract dye (Annatto (Bixa Orellana)) and FD\&C Blue No. 1.

OTHER

Non-plaque disclosing toothpaste

Toothpaste that does not contain the FDA-registered seed-extract dye (Annatto (Bixa Orellana)) and FD\&C Blue No. 1.

Sponsors & Collaborators

  • University of Wisconsin, Madison

    collaborator OTHER

  • Marshfield Clinic Research Foundation

    lead OTHER

Principal Investigators

  • Amit Acharya, BDS, MS, PhD · Marshfield Clinic Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
84 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-17
Primary Completion
2019-12-30
Completion
2019-12-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03641989 on ClinicalTrials.gov