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Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers

NCT02670135 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 303

Last updated 2019-02-22

No results posted yet for this study

Summary

This is a single center, double blinded, randomized, controlled trial. Qualified subjects will be enrolled and randomized to either one of the two study groups: a) using 0.3% triclosan/copolymer/fluoride dentifrice twice daily - b) using a matching control dentifrice (copolymer/fluoride/no triclosan) twice daily.

Conditions

  • Periodontal Disease
  • Systemic Inflammatory Markers

Interventions

DRUG

Triclosan Containing Toothpaste

Active formula containing 0.3% triclosan in a1450 ppm sodium fluoride/silica base

DRUG

Triclosan Free Toothpaste

Control toothpaste with no triclosan ingredients in a 1450 ppm sodium fluoride/silica base - matching placebo

Sponsors & Collaborators

  • Colgate Palmolive

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-06-30
Primary Completion
2016-07-31
Completion
2016-08-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02670135 on ClinicalTrials.gov