MedTrace Logo

Variation in Gingival Inflammatory Responses

NCT05968742 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2025-11-13

No results posted yet for this study

Summary

The aim of this NIH National Institute of Dental and Craniofacial Research (NIDCR) funded study is to identify molecular mechanisms underlying observed variations in human responses to natural accumulation and maturation of dental plaque.

Conditions

  • Gingivitis

Interventions

BEHAVIORAL

Abstinence of oral hygiene on select teeth

Study participants abstain from oral hygiene on a select set of four teeth for a period of 21 days

Sponsors & Collaborators

Principal Investigators

  • Jeffrey S McLean, PhD · University of Washington

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-30
Primary Completion
2026-10-01
Completion
2027-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05968742 on ClinicalTrials.gov