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A Study to Evaluate the Effect of a Stannous Fluoride Toothpaste on the Oral Microbiome

NCT06048809 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2025-07-10

Study results available
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Summary

The aim of this study is to evaluate the effect of a toothpaste containing stannous fluoride (SnF2) over time on the oral bacterial composition and activity and to explore its effect in comparison to a regular fluoride toothpaste.

Conditions

  • Oral Health

Interventions

OTHER

Stannous Fluoride Toothpaste (Sensodyne Repair and Protect)

Sensodyne Repair and Protect toothpaste containing 1100 ppm fluoride as SnF2.

OTHER

Regular Fluoride Toothpaste (Colgate Cavity Protection)

Colgate Cavity Protection containing 1100 ppm fluoride as SMFP.

Sponsors & Collaborators

  • HALEON

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-04-10
Primary Completion
2024-05-30
Completion
2024-05-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06048809 on ClinicalTrials.gov